Journal: Der Kardiologe

Article Title: Manual der Arbeitsgruppe Interventionelle Kardiologie (AGIK) der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. (DGK)

doi: 10.1007/s12181-021-00493-6

Figure Lengend Snippet:

Article Snippet: , , , Iomeprol (Imeron®, Bracco Imaging Deutschland GmbH, Konstanz, Deutschland).

Techniques: Imaging

Journal: European Radiology Experimental

Article Title: The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

doi: 10.1186/s41747-018-0069-y

Figure Lengend Snippet: List of contrast agents applied in this in vitro study

Article Snippet: CT , Iomeprol , Imeron 300 M (Bracco Imaging, Konstanz, Germany) , Monomeric, nonionic , 300 mg iodine/mL , 521 , 2.9 , Renal.

Techniques: In Vitro, Concentration Assay, Viscosity, Imaging

Journal: European Radiology Experimental

Article Title: The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

doi: 10.1186/s41747-018-0069-y

Figure Lengend Snippet: Genotoxic and cytotoxic impact of contrast-enhanced CT exposure. Isolated lymphocytes were incubated with indicated concentrations of iomeprol or iopromid. Samples incubated in cell culture medium only ( neg. ctrl ) or with mannitol solution with the same osmolality as iopromide (590 mOsm/kg H 2 O) served as negative controls. Additionally, samples were either irradiated by a thorax CT scan ( + ) or placed outside the CT scanner (-) at the same temperature. a The level of DNA double-strand breaks was assessed 15 min after CT exposure by γH2AX staining and automated foci quantification. Lymphocytes irradiated with 0.5 Gy served as positive controls ( pos. ctrl ). b Apoptosis rate was quantified after 24 h by Annexin V/propidium iodide staining combined with flow cytometric analysis. Samples incubated with 2 μM camptothecin served as positive controls. c For proliferation analysis, lymphocytes were activated with PHA directly after CT exposure. Level of DNA synthesis was determined after 72 h by [ 3 H]-thymidine incorporation. Lymphocytes treated with 2 μM camptothecin served as positive controls. Diagrams displays mean ± standard error of the mean of four experiments (*** p ≤ 0.001; ** p ≤ 0.01; * p ≤ 0.05) and raw data are listed in Additional file : Tables S1–S3

Article Snippet: CT , Iomeprol , Imeron 300 M (Bracco Imaging, Konstanz, Germany) , Monomeric, nonionic , 300 mg iodine/mL , 521 , 2.9 , Renal.

Techniques: Isolation, Incubation, Cell Culture, Irradiation, Computed Tomography, Staining, DNA Synthesis